While all layouts are using the same content elements, they are making use of media assets differently. For example - when using a horizontal image or video - it’s better the avoid using a full-bleed layout, that’s likely to discard the content on the sides.
How to access: Story Editor > Layouts and Presets tab on the right side
Layouts do not carry colours or fonts presets. To create such presets - please use the Skins tab in the Layouts and Presets section.
Tip: Alternating layouts across your story will keep your users engaged for longer and will make your story more exciting to explore.